This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. ATTENTION: If you speak a language other than English, language assistance services are available to you free of charge. Blue Cross Blue Shield of Massachusetts is an Independent Licensee of the Blue Cross and Blue Shield Association.

Sildenafil 10mg can cause dizziness or vision changes in some users.
Always check for drug interactions before taking sildenafil.
It is important to stay hydrated when using sildenafil.
The medication is not effective as an aphrodisiac without stimulation.
Seek emergency help if you experience chest pain after use.

® Registered Marks of the Blue Cross and Blue Shield Association.

Other targets: Side effects

You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Does the price of sildenafil vary based on strength or what it is prescribed for?

Before using this medication, tell your doctor or sildenafil uk price pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) other lung conditions (such as pulmonary veno-occlusive disease) This drug may make you dizzy or cause vision problems. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Starting Sildenafil: Recommended First-Time Dosage

During pregnancy, sildenafil should be used only when clearly needed. Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, discuss with your doctor right away the benefits and risks of using this medication during pregnancy. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. ®´ Registered Marks of Blue Cross and Blue Shield of Massachusetts, Inc., or Blue Cross and Blue Shield of Massachusetts HMO Blue, Inc. ®´´ Registered Marks, TM Trademarks, and SM Service Marks are the property of their respective owners.

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13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Endothelial friendly

Rarely, sudden decreased vision, or even permanent blindness, may occur in one or both eyes (NAION). If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke. Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur.

Still not finding the right product?

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. Get medical help right away if you have any very serious side effects, including: increased shortness of breath or trouble breathing A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. ® Registered Marks and SM Service Marks of the Blue Cross and Blue Shield Association.

Other targets: Therapeutic roles

Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting.

The Bottom Line

Your doctor may adjust your medications to minimize your risk of low blood pressure. Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works. Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away.

What Are the Available Sildenafil Dosages?

US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669. Symptoms of overdose may include: dizziness, fainting, painful/prolonged erection. Do not share this medication with others. Lab and/or medical tests (such as eye exams, blood pressure) may be done while you are taking this medication. ®´ Registered Marks of Blue Cross Blue Shield of Massachusetts, Inc.

What is sildenafil?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. Different brands of this medication have different storage needs.

How do the side effects compare for vardenafil and sildenafil?

Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. ®´ Registered Marks, TM Trademarks, and SM Service Marks are property of their respective owners.

Erectile dysfunction can be caused by various medical conditions; discuss treatment options with a doctor.
The medication is generally well-tolerated but requires medical supervision.
Side effects can include indigestion, muscle aches, or flushing.
Avoid using sildenafil if you are pregnant or breastfeeding.
Proper dosage and timing maximize the benefits of sildenafil 10mg.

If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL INJECTION safely and effectively.

The drug is generally safe when used as prescribed.
Patients should inform their doctor about all health conditions.
Sildenafil 10mg is sometimes used to treat high-altitude pulmonary hypertension.
Do not take sildenafil with heavy or fatty foods for better absorption.
Store the medication at room temperature away from moisture.

See full prescribing information for SILDENAFIL INJECTION.SILDENAFIL injection, for intravenous useInitial U.S.

Medication effectiveness can be impacted by certain health conditions.
Men should not use sildenafil if they have a history of stroke.
Sildenafil 10mg can sometimes cause nasal congestion.
It’s important to report any unusual side effects to your doctor.
Do not use sildenafil if you are taking other ED medications.

Approval: 1998INDICATIONS AND USAGEAdultsSildenafil injection is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening.

Condition	Risk Factors	Recommendations
Use with nitrates	Severe hypotension, risk of significant blood pressure drop	Avoid combining, consult healthcare provider
Severe cardiovascular disease	Risk of adverse cardiovascular events	Use only under medical supervision
Liver impairment	Altered metabolism, increased side effects	Dose adjustment or avoid use
Retinitis pigmentosa	Potential for increased visual side effects	Use with caution, consult ophthalmologist

(1)DOSAGE AND ADMINISTRATIONInjection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1)DOSAGE FORMS AND STRENGTHSInjection: 10 mg/12.5 mL in a single-dose vial (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs.

Understanding Tadalafil and Sildenafil

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional sildenafil tablet manforce 50 mg for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises.

Side Effect	Severity	Likelihood	Management Tips
Headache	Mild to moderate	Common	Mild analgesics, hydration
Flushing	Mild	Common	Cool environment, stay hydrated
Nasal congestion	Mild	Moderately common	Decongestants if necessary
Dizziness	Mild	Possible	Avoid sudden movements
Visual disturbances	Mild	Rare	Rest and monitor if occurs

(5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended.

Parameter	Value	Notes
Absorption Rate	Rapid	Peak plasma levels in ~60 minutes
Bioavailability	Approximately 40%	Due to first-pass metabolism
Half-life	About 4 hours	Time to reduce plasma concentration by half
Metabolism	Liver (primarily via CYP3A4)	Enzymatic breakdown
Excretion	Mainly feces (~80%)	Some via urine (~13%)

(7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. (5.6)Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil). However, due to Viatris Specialty LLC's marketing exclusivity rights, this drug product is not labeled with that information.See 17 for PATIENT COUNSELING INFORMATION.Revised: 12/2023 Injection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1) Injection: 10 mg/12.5 mL in a single-dose vial (3) Vasodilation effects may be more common in patients with hypotension or on antihypertensive therapy.

Viagra and health: Beyond ED