Label: VARDENAFIL tablet, orally disintegrating

Vardenafil hydrochloride orally disintegrating tablets must be used only under a doctor’s care.HOW DOES VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS WORK?When a man is sexually stimulated, his body’s normal physical response is to increase blood flow to his penis.

14.1 Other Vardenafil Clinical Trials Using Film-Coated Tablets

Vardenafil hydrochloride orally disintegrating tablets must be used only under a doctor’s care.HOW DOES VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS WORK?When a man is sexually stimulated, his body’s normal physical response is to increase blood flow to his penis. Vardenafil hydrochloride orally disintegrating tablets helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.WHO CAN TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Talk to your doctor to decide if vardenafil hydrochloride orally disintegrating tablets are right for you.Vardenafil hydrochloride orally disintegrating tablets have been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes.WHO SHOULD NOT TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Do not take vardenafil hydrochloride orally disintegrating tablets if you:· Take any medicines called “nitrates” (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”). Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches.

How long before sex should I take vardenafil?

Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use vardenafil hydrochloride orally disintegrating tablets if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.· Take riociguat, a guanylate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-throembolic pulmonary hypertension.· Have been told by your healthcare provider to not have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.WHAT SHOULD YOU DISCUSS WITH YOUR DOCTOR BEFORE TAKING VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Vardenafil hydrochloride orally disintegrating tablets helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.WHO CAN TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Talk to your doctor to decide if vardenafil hydrochloride orally disintegrating tablets are right for you.Vardenafil hydrochloride orally disintegrating tablets have been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes.WHO SHOULD NOT TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Do not take vardenafil hydrochloride orally disintegrating tablets if you:· Take any medicines called “nitrates” (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”). Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use vardenafil hydrochloride orally disintegrating tablets if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.· Take riociguat, a guanylate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-throembolic pulmonary hypertension.· Have been told by your healthcare provider to not have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.WHAT SHOULD YOU DISCUSS WITH YOUR DOCTOR BEFORE TAKING VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Before taking vardenafil hydrochloride orally disintegrating tablets, tell your doctor about all your medical problems, including if you:· Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity.· Have low blood pressure or have high blood pressure that is not controlled.· Have pulmonary hypertension· Have had a stroke.· Have had a seizure.· Or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome).· Have liver problems.· Have kidney problems and require dialysis.· Have retinitis pigmentosa, a rare genetic (runs in families) eye disease.· Have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION).· Have stomach ulcers.· Have a bleeding problem.· Have a deformed penis shape or Peyronie’s disease.· Have had an erection that lasted more than 4 hours.· Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia.· Have hearing problems.· Have phenylketonuria.· Have fructose intolerance.CAN OTHER MEDICATIONS AFFECT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Product	Dosage	Quantity + Bonus	Price
Priligy Generic Dapoxetine	60mg	30 + 6 Pills	106.65€ 101.57€	Buy
Cialis Super Active	20mg	120 + 16 Pills	382.15€ 363.95€	Buy
Cialis Generic	60mg	360 + 10 Pills	570.52€ 543.35€	Buy
Cialis Professional	40mg	270 + 6 Pills	898.37€ 855.59€	Buy
Viagra Generic	50mg	180 + 8 Pills	158.82€ 151.26€	Buy
Priligy Generic Dapoxetine	60mg	10 Pills	47.63€ 45.36€	Buy
Levitra Generic	20mg	60 + 6 Pills	131.11€ 124.87€	Buy
Levitra Generic	60mg	30 + 2 Pills	109.43€ 104.22€	Buy
Kamagra Gold	100 mg	32 Pills	121.24€ 115.47€	Buy
Super Kamagra	160 mg	20 + 4 Pills	155.35€ 147.95€	Buy
Kamagra Soft Tabs	100 mg	180 + 8 Pills	425.45€ 405.19€	Buy
Viagra Generic	50mg	20 Pills	40.52€ 38.59€	Buy
Viagra Generic	50mg	360 + 10 Pills	225.33€ 214.60€	Buy
Viagra Generic	200mg	270 + 10 Pills	379.76€ 361.68€	Buy
Kamagra 100 mg	100 mg	32 Pills	121.24€ 115.47€	Buy

Vardenafil hydrochloride orally disintegrating tablets and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines.

5.8 Hepatic Impairment

If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis including the inability to have erections.· Color vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green.In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including vardenafil) reported a sudden decrease or loss of vision in one or both eyes. It is uncertain whether PDE5 inhibitors directly cause the vision loss. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including vardenafil hydrochloride orally disintegrating tablets, and call a doctor right away.Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including vardenafil. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors.

What should I do if I get chest pain after taking vardenafil?

If you experience these symptoms, stop taking vardenafil hydrochloride orally disintegrating tablets and contact a doctor right away.These are not all the side effects of vardenafil hydrochloride orally disintegrating tablets. For more information, ask your doctor or pharmacist.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA 1088.HOW SHOULD VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING Tablets BE STORED?· Store vardenafil hydrochloride orally disintegrating tablets at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature].· Keep vardenafil hydrochloride orally disintegrating tablets and all medicines out of the reach of children.GENERAL INFORMATION ABOUT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETSMedicines are sometimes prescribed for conditions other than those described in patient information leaflets. Do not use vardenafil hydrochloride orally disintegrating tablets for a condition for which it was not prescribed. Do not give vardenafil hydrochloride orally disintegrating tablets to other people, even if they have the same symptoms that you have. Especially tell your doctor if you take any of the following:· Medicines called nitrates (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”).• Medicines containing cobicistat.· Medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone and sotalol.· Ritonavir (Norvir®) or indinavir sulfate (Crixivan®) saquinavir (Fortavase® or Invirase®) or atazanavir (Reyataz®) or other HIV protease inhibitors.· Ketoconazole or itraconazole (such as Nizoral® or Sporanox®).• Cobicistat· Erythromycin or clarithromycin.· Other medicines or treatments for ED.Patients taking these drugs should not use vardenafil hydrochloride orally disintegrating tablets.Patients taking alpha-blockers should not initiate vardenafil therapy with vardenafil hydrochloride orally disintegrating tablets.

Brand Name	Price per Pack	Dosage Options	Over-the-counter (OTC)	Prescription Required
Levitra	$40-$60	5, 10, 20 mg	No	Yes
Vardenafil Generic	$10-$25	5, 10, 20 mg	No	Yes
Other Brands	Varies	5-20 mg	No	Yes

Patients taking alpha-blockers who have previously used vardenafil film-coated tablets may switch to vardenafil hydrochloride orally disintegrating tablets at the advice of their healthcare provider.· Medicines called alpha-blockers. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients the use of PDE5 inhibitor drugs, including vardenafil hydrochloride orally disintegrating tablets, with alpha-blockers can lower blood pressure significantly leading to fainting.· Patients should contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider.HOW SHOULD YOU TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Take vardenafil hydrochloride orally disintegrating tablets exactly as your doctor prescribes. Vardenafil hydrochloride orally disintegrating tablets tadalis oral jelly comes in 10 mg orally disintegrating tablets. The dose is one vardenafil hydrochloride orally disintegrating tablet. Do not take more than one vardenafil hydrochloride orally disintegrating tablet a day.

Affordable men's sexual healthcare you can trust.

The dose is one vardenafil hydrochloride orally disintegrating tablet. Do not take more than one vardenafil hydrochloride orally disintegrating tablet a day. Doses should be taken at least 24 hours apart.· If you have prostate problems or high blood pressure, for which you take medicines called alpha-blockers, you should not start treatment for erectile dysfunction with vardenafil hydrochloride orally disintegrating tablets. Your doctor may prescribe a lower dose of vardenafil film-coated tablet.Take 1 vardenafil hydrochloride orally disintegrating tablet about 1 hour (60 min) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with vardenafil hydrochloride orally disintegrating tablets.

What medicines should never be taken with vardenafil?

Vardenafil hydrochloride orally disintegrating tablets may be taken with or without meals.Place on the tongue where it will dissolve rapidly. The tablet should be taken whole and not crushed or split.The tablet should not be taken with liquid.It should be taken immediately upon removal from the blister.Call your doctor or emergency room immediately if you accidentally took more vardenafil hydrochloride orally disintegrating tablets than prescribed.If you receive vardenafil hydrochloride orally disintegrating tablets in a blisterpack, examine the blisterpack before use. Do not use if blisters are torn, broken, or missing.WHAT ARE THE POSSIBLE SIDE EFFECTS OF VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?The most common side effects with vardenafil hydrochloride orally disintegrating tablets are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness, and back pain. These side effects usually go away after a few hours. Call your doctor if you get a side effect that bothers you or one that will not go away.Vardenafil hydrochloride orally disintegrating tablets may uncommonly cause:· An erection that won’t go away (priapism). Doses should be taken at least 24 hours apart.· If you have prostate problems or high blood pressure, for which you take medicines called alpha-blockers, you should not start treatment for erectile dysfunction with vardenafil hydrochloride orally disintegrating tablets. Your doctor may prescribe a lower dose of vardenafil film-coated tablet.Take 1 vardenafil hydrochloride orally disintegrating tablet about 1 hour (60 min) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with vardenafil hydrochloride orally disintegrating tablets. Vardenafil hydrochloride orally disintegrating tablets may be taken with or without meals.Place on the tongue where it will dissolve rapidly.

• Vardenafil is effective for up to 4-5 hours.
• Do not use if allergic to vardenafil or similar drugs.
• Overdose symptoms may include prolonged erections.
• Medical advice is essential for any severe side effects.

The tablet should be taken whole and not crushed or split.The tablet should not be taken with liquid.It should be taken immediately upon removal from the blister.Call your doctor or emergency room immediately if you accidentally took more vardenafil hydrochloride orally disintegrating tablets than prescribed.If you receive vardenafil hydrochloride orally disintegrating tablets in a blisterpack, examine the blisterpack before use. Do not use if blisters are torn, broken, or missing.WHAT ARE THE POSSIBLE SIDE EFFECTS OF VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?The most common side effects with vardenafil hydrochloride orally disintegrating tablets are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness, and back pain. These side effects usually go away after a few hours. Call your doctor if you get a side effect that bothers you or one that will not go away.Vardenafil hydrochloride orally disintegrating tablets may uncommonly cause:· An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away.

• Vardenafil is sometimes prescribed off-label for pulmonary hypertension.
• It is not suitable for women or children.
• Patients should report any unexplained vision loss.
• Avoid using grapefruit juice with vardenafil.

Priapism must be treated as soon as possible or lasting damage can happen to your penis including the inability to have erections.· Color vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green.In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including vardenafil) reported a sudden decrease or loss of vision in one or both eyes.

Dosage (mg)	Typical Usage	Onset of Action	Duration of Effect
10	Mild to moderate ED	30-60 minutes	Up to 4 hours
20	Moderate to severe ED	30-60 minutes	Up to 4-5 hours
5	Lower dose for less side effects	30-60 minutes	Up to 4 hours
25	Off-label use, clinical trials	30-60 minutes	Up to 4 hours

It is uncertain whether PDE5 inhibitors directly cause the vision loss. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including vardenafil hydrochloride orally disintegrating tablets, and call a doctor right away.Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including vardenafil. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors.

What special dietary instructions should I follow?

It may harm them.This leaflet summarizes the most important information about vardenafil hydrochloride orally disintegrating tablets.

Related treatment guides

If you experience these symptoms, stop taking vardenafil hydrochloride orally disintegrating tablets and contact a doctor right away.These are not all the side effects of vardenafil hydrochloride orally disintegrating tablets.

4.1 Nitrates

Before taking vardenafil hydrochloride orally disintegrating tablets, tell your doctor about all your medical problems, including if you:· Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity.· Have low blood pressure or have high blood pressure that is not controlled.· Have pulmonary hypertension· Have had a stroke.· Have had a seizure.· Or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome).· Have liver problems.· Have kidney problems and require dialysis.· Have retinitis pigmentosa, a rare genetic (runs in families) eye disease.· Have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION).· Have stomach ulcers.· Have a bleeding problem.· Have a deformed penis shape or Peyronie’s disease.· Have had an erection that lasted more than 4 hours.· Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia.· Have hearing problems.· Have phenylketonuria.· Have fructose intolerance.CAN OTHER MEDICATIONS AFFECT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Vardenafil hydrochloride orally disintegrating tablets and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines. Especially tell your doctor if you take any of the following:· Medicines called nitrates (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”).• Medicines containing cobicistat.· Medicines that treat abnormal heartbeat.

Are you currently using Vardenafil (Levitra, Staxyn)?

These include quinidine, procainamide, amiodarone and sotalol.· Ritonavir (Norvir®) or indinavir sulfate (Crixivan®) saquinavir (Fortavase® or Invirase®) or atazanavir (Reyataz®) or other HIV protease inhibitors.· Ketoconazole or itraconazole (such as Nizoral® or Sporanox®).• Cobicistat· Erythromycin or clarithromycin.· Other medicines or treatments for ED.Patients taking these drugs should not use vardenafil hydrochloride orally disintegrating tablets.Patients taking alpha-blockers should not initiate vardenafil therapy with vardenafil hydrochloride orally disintegrating tablets. Patients taking alpha-blockers who have previously used vardenafil film-coated tablets may switch to vardenafil hydrochloride orally disintegrating tablets at the advice of their healthcare provider.· Medicines called alpha-blockers. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients the use of PDE5 inhibitor drugs, including vardenafil hydrochloride orally disintegrating tablets, with alpha-blockers can lower blood pressure significantly leading to fainting.· Patients should contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider.HOW SHOULD YOU TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?Take vardenafil hydrochloride orally disintegrating tablets exactly as your doctor prescribes. Vardenafil hydrochloride orally disintegrating tablets tadalis oral jelly comes in 10 mg orally disintegrating tablets. For more information, ask your doctor or pharmacist.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA 1088.HOW SHOULD VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING Tablets BE STORED?· Store vardenafil hydrochloride orally disintegrating tablets at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature].· Keep vardenafil hydrochloride orally disintegrating tablets and all medicines out of the reach of children.GENERAL INFORMATION ABOUT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETSMedicines are sometimes prescribed for conditions other than those described in patient information leaflets.

8.4 Pediatric Use

What are the most common side effects of vardenafil?

Do not use vardenafil hydrochloride orally disintegrating tablets for a condition for which it was not prescribed.

Drug Category	Potential Interaction	Effect
Nitrates	Dangerous hypotension	Severe decrease in blood pressure
CYP3A4 Inhibitors	Increased vardenafil levels	Increased side effects
Alpha-blockers	Risk of hypotension	Dizziness, fainting
Pesticides (e.g., erythromycin)	Possible increased plasma levels	Enhanced side effects

Do not give vardenafil hydrochloride orally disintegrating tablets to other people, even if they have the same symptoms that you have. It may harm them.This leaflet summarizes the most important information about vardenafil hydrochloride orally disintegrating tablets.